Several people – including some armed with clubs – climbed on top of the old Cornerhouse cinema on Oxford Road, bring the busy area to a standstill at lunchtime.
Police cordoned off the area, and closed Whitworth St West, with one man appearing to have a rope around his neck attached to a sign on top of the building.
It is not clear whether the men are in any way connected to the band of squatters who occupied the space in March this year, turning it into a temporary art gallery called ‘Loose Space.’
There was disruption to services in and out of Oxford Road as a result.