Flood warnings are being issued across Greater Manchester as heavy rain and wind are set to batter the North West.
The Met Office declared a severe weather warning as up to four inches of rain is expected for some areas.
The excess amount could become surface water and flood roads, land and cause concerns for rivers in built-up areas.
The agency is urging people in Greater Manchester, Liverpool, the Wirral, North Cheshire and Lancashire to be prepared for the possibility of flooding until Saturday.
Matt Dobson, a forecaster with the Press Association’s Meteogroup, said: "The worst weather overnight has been across the North West and into Cheshire, where between 10-20mm (0.4-0.8 inches) fell. Central and southern Scotland were also badly hit.
"Throughout the day the rain really is going to develop from South West Scotland, across Northern Ireland down into north-west England.
"It will be very wet in those areas, with the worst of it in Cumbria and the western Pennines, from Manchester up to Cumbria and across into south-west Scotland, and in north-west Wales as well.
"There will be 20-30mm (0.8-1.2 inches) of rain quite widely, with maybe as much as 50-60mm (2-2.4 inches) of rain over upland areas such as the fells of Cumbria and the western Pennines."
Flood defences are being checked by the Environmental Agency and river blockages are also being cleared.
People are being warned to avoid swollen rivers and driving through floodwater.