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There will be a number of events hosted across the city.
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Space geeks ran amok in the Museum of Science and Industry on Friday night as the space-tacular live show Out of this World came to Manchester.
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MM's Andrew Little finds out that Your Days Are Numbered go far beyond your average comedy show
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The warm up for Manchester Science Festival begins this week with a live comedy show featuring Professor Brian Cox.
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Young people are being challenged to dream up their Manchester of the future in a bid to spark a passion in science and the arts.
